Category
Orthopedic Biomaterial
Typical Use
Provide osteoconductive scaffold or osteoinductive factors when autograft is limited.
Description
Synthetic or biologic materials such as calcium phosphate ceramics, demineralized bone matrix, or recombinant growth factors used to augment or replace autologous bone graft in spinal fusion, fracture repair, and reconstructive surgery, offering off the shelf options that reduce donor site morbidity. Selection depends on defect size, biologic activity required, and regulatory approvals, and combination strategies with autograft or cell based therapies may enhance outcomes. Clinical evidence, cost, and patient specific factors guide substitute choice, and surgeons monitor incorporation and fusion success through imaging and functional assessment.